Services
Alveolar macrophage assessments for translational approached studies and regulatory applications
Immune response and inflammatory mediator biochemistry
Preclinical assessment of novel compounds and test articles
Comprehensive technical support and rapid data turnaround times
- Dose response and IC50
- Inhalation Toxicology
- Concentration selection
- Viability
- Functionality and mechanistic endpoints (phagocytosis)
- Cytotoxicity
- Permeation and transport studies
- Morphology
- CD markers, cytokine arrays, advance profiling
- Alveolar clearance
- Macrophage polarisation
- Macrophage recovery
- Irritation
- Sensitisation
- Multiple molecule/compound assessments
- High content image analysis
- Cell morphology studies for quantified cell and nuclear size, vacuolation
- Cell health mitochondrial activity and membrane permeability
- Cell mechanistic phospholipids, steatosis
- Population response
- Individual cell analysis and phenotype profiles
- Morphological comparisons
- With you every step of the way from understanding your needs and goals, study design to scientific reporting
- Proof of concept studies
- International collaborative projects
- Innovation and translational sciences
- Training development