Currently, there is an increasing interest in moving away from animal research by incorporating the 3R approach (Animal Replacement, Reduction, Refinement). Furthermore, human cell culture assays have demonstrated the potential to represent human-relevant responses rapidly and more accurately.
ImmuONE is developing animal-free products for ImmuLUNG™ and ImmuPHAGE™ by substituting foetal bovine serum (FBS) for chemically defined serum (CDS) to support a more fitting approach that also enables the manufacturing a standardised in vitro mode with reproducible results. Our preliminary studies show that our immune cells can be safely cultured in animal product free medium whilst maintaining equivalent health, morphology and functionality.