Screening & Discovery

We have developed our own in-house immunocompetent cell culture product of the alveolus for next generation inhalation risk assessment. ImmuPHAGE is a robust and reproducible model of human alveolar-like macrophages which closely resembles in vivo morphology, biochemistry and functionality. Our patented system, ImmuLUNGTM is our human alveolar tissue model comprising alveolar epithelial cells and alveolar-like macrophages in co-culture, and able to provide a detailed understanding of immune and barrier responses in the airways.

We provide in vitro testing services and source commercially available products (e.g., organ-on-chip models) for respiratory assessments by identifying relevant technologies tailored to your needs.

• Dose response (IC50) and selection
• Inhalation toxicology
• Cell health and morphology
• Functionality and mechanistic studies (e.g. phagocytosis)
• Permeation and transport studies