IN-HOUSE Solutions AT IMMUONE
Specialists in in-vitro inhalation and immune toxicology spanning the entire length of the respiratory tract from nose to alveolus.
ImmuONE offers innovative independent toxicology laboratory services to help you understand and identify the safety and efficacy of your products in the lungs using in vitro, non-clinical assessment strategies.
Based in the UK, we offer our customers a range of advanced toxicology testing services from standardised methods (such as tissue irritation and cell permeability) to advanced and bespoke assessment strategies (e.g. cell-response phenotyping).
We use a variety of proprietary, non-proprietary and in-house developed in vitro cell culture models to provide the best human physiological relevance for safety assessment. We also work with established animal cell line models to support the translation of in vivo studies.
NAVIGATE AND STREAMLINE INHALED PRODUCT SAFETY DECISIONS
ImmuONE team of specialists can help you carefully navigate safety decisions and streamline the pre-clinical process for drug and assay development in support of inhalation and immune toxicity testing. Our general toxicology laboratory services include:
- Assay development
- Inflammation and immune response
- Profiling Macrophage Responses Using High-Content Image Analysis
- Inhalation toxicology
- Animal product-free toxicology services
- Drug Discovery Screening
- Drug development
- Therapeutic areas
More About our services
Assay development
On-demand cell assay development tailored to your toxicity testing needs.
In vitro methods offer vast potential to support specific inhalation testing techniques, but standardised assessment approaches remain limited. We will help you navigate the available standardised in vitro preclinical testing services or create bespoke assays designed to meet your specific requirements.
Inflammation and immune response
Specialists in alveolar macrophage response assays
Using our standardised in vitro models, we’ll help you understand the variety of inflammatory and immunological responses that can manifest in the airways. Our innovative in vitro solutions can predict lung-related inflammatory responses.
Profiling Macrophage Responses Using High-Content Image Analysis
High content imaging to determine adaptive and adverse immune responses
High Content Image Analysis (HCIA) provides a comprehensive assessment of various cellular endpoints, enabling precise evaluation of cell health, inflammation, morphology, and functional responses. This advanced imaging technique offers in-depth insights into cellular behavior, facilitating more accurate and reliable interpretations of complex biological processes
Inhalation toxicology
Transforming inhalation testing techniques
How can you be sure your chemical or product doesn’t present an inhalation risk? At ImmuONE, we’re developing and advancing in vitro inhalation testing techniques to cut the cost of improving inhaled product safety, efficacy and validation.
Animal product-free toxicology services
Driving the shift towards human-relevant safety assessments free from animal-derived products
One of our biggest research interests is adapting assays to be free of animal-derived products. Discover what we’re doing to create more ethically conscious independent toxicology testing services.
Drug Discovery Screening
Accelerating the progress of promising drugs through the development pipeline
Our drug screening services ensure preclinical candidates have the optimal properties for success.
Drug development
Expert support in understanding inhaled product efficacy and safety
ImmuONE provides expert guidance in understanding the fate of inhaled products, from aerosolisation to deposition in the airways and their interaction with the biological substrates of the respiratory system.
Therapeutic areas
We are expanding our preclinical toxicity services to other organs and diseases
Talk to us about designing tailor-made assessments for where tissue-resident macrophage responses can provide valuable insights into human safety (e.g. lung diseases, the eye and atherosclerosis).
FIND OUT MORE THROUGH OUR LATEST WEBINAR
