Gender equality in the biotech industry has come a long way in recent years. In the UK, the US and Europe, women now make up between 40-50% of the biotech workforce, which is a higher percentage than in other STEM fields, such as engineering and the physical sciences.
The ImmuLUNG™ cell model developed by ImmuONE can help predict how lung epithelial and immune cells respond to inhaled substances. Used in-house as part of ImmuONE’s services, ImmuLUNG™ combines human alveolar epithelial cells and alveolar macrophage-like cells in a 3D environment.
Human alveolar-like macrophages
Human alveolar epithelial cells
WHAT IS IMMULUNG™?
ImmuLUNG™ combines human alveolar epithelial cells and alveolar macrophage-like cells in a 3D environment. The interactions between these two cell types provide better physiological representation, enabling a more accurate and in-depth understanding of how inhaled products interact with the airways in the deep lung.
Key Features and Benefits:
How it works
The model is composed of alveolar macrophage-like cells assembled in vitro in well plates, that closely represent the form and function of human cells. Substances are added to the well plates, and adverse responses can then be evaluated. ImmuPHAGE™ is fully validated and characterised for cell structure & viability, phagocytic activity and cytokine response. ImmuPHAGE™ is available for purchase as a product and as part of ImmuONE’s service packages.
Watch our video below to see how to use ImmuPHAGE™
How it works
ImmuLUNG™ combines human alveolar epithelial cells and alveolar macrophage-like cells in a 3D environment. The resulting cellular crosstalk can better recreate lung tissue functions and immune response modulations.
Available as an in-house service at ImmuONE, these immortalised human alveolar epithelial and macrophage-like cells are preassembled on tissue culture well plates. A range of test materials can be applied to the model in solution, suspension or as an aerosol, and the biological responses of individual cells or the whole system can be monitored.
ImmuLUNG™ is currently available as part of ImmuONE’s service packages – coming soon as a standalone product.
USES FOR IMMULUNG™
Advantages of using ImmuLUNG™
Available formats for ImmuLUNG™
By default, ImmuLUNGis available in an air-liquid interface 24-well format for our in-house services. Other formats are available on request.
Find out more
New innovations, new research, new teammates, a new lab – and soon, a new year! Before we turn our attention to 2024, let’s take a step back and appreciate all we’ve achieved so far.
ImmuONE made a significant stride on November 8th by hosting its first-ever webinar, ‘unveiling insights into the next generation of tools for inhalation risk assessment’. The webinar began with a glimpse into ImmuONE’s evolution, emphasizing key milestones and leadership perspectives, presented by Prof. Victoria Hutter.