A coffee with Rhamiya: Being an application scientist
In our latest coffee chat, we had the pleasure of sitting down with Rhamiya Mahendran, an Application Scientist at ImmuONE…
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News
Why in vitro methods are the future of risk assessments for inhaled substances
Inhaled substances are primarily tested on rats for toxicity, but key differences between rat and human lungs suggest it’s time to look towards alternative methods.
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Reliable, reproducible, robust: morph_ONE for high content image analysis of the lung
morph_ONE is a reproducible, mechanistic-driven assay that reveals how inhaled substances affect more than a dozen morphological and biochemical features of alveolar macrophages. The assay helps companies and researchers to correctly interpret the response of the immune system in the lungs to inhaled chemical products, improving product development and ensuring safety as well as saving time and money.
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Improving safety assessments of inhaled drugs with ImmuONE’s high content image analysis approaches
More than half of aerosol medicines under development are terminated due to safety concerns. ImmuONE’s high content imaging or cell painting assays are proven to accurately predict the safety of inhaled compounds by quantifying mechanism-linked morphological and biochemical characteristics within cells, contributing to faster, more informed decision making in the early stages of inhaled drug development.
Rapid Fire Round with Nilab Haydare: Life at ImmuONE
Q: What attracted you to ImmuONE as a company?
A: I was initially drawn to ImmuONE because of my positive experience during my final year dissertation, where I worked on cell culture skills with Dr. Victoria Hutter…
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ImmuONE announces launch of first product ImmuPHAGE™ to understand the safety of inhaled substances in vitro
ImmuONE today announced the launch of ImmuPHAGE™, an in vitro assay that can evaluate how substances interact with the macrophage white blood cells found in the deep lung’s alveoli.
Successful adaptation of TK6 cells to an animal-product-free culture medium
Foetal bovine serum (FBS) is widely used in cell culture media, but may limit the human relevance of safety assessments. A new study demonstrates the successful transition of the TK6 cell line to an FBS-free medium.
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Q&A: Applying ImmuLUNG™ on ‘organ-on-a-chip’ platforms
Nilab Haydare is a pre-clinical scientist at ImmuONE specialising in in-vitro toxicology research. She will be presenting the poster of her study,…
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Incorporating New Approach Methodologies
Despite the increasing power of non-animal approaches, the move towards their inclusion in pharmaceutical safety testing is slow, largely due to a lack of familiarity among regulators.
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Immune cells show difference between e-cigarette and cigarette exposure
New research demonstrates how an analytical technique known as morphometric phenotyping can distinguish between the effects of different nicotine products on immune cells.
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