Human cell culture solutions for safety assessments

In vitro specialists for immune responses in the lung

What kind of macrophage are you?

What is ImmuONE?

ImmuONE delivers innovative respiratory in vitro cell culture products and services focusing on immune system reactions

Our approach is threefold

Bespoke risk assessment services

Bespoke risk assessment services

Our bespoke services offer a personalised, human-relevant in vitro solution that uniquely addresses your risk assessment needs

Multi-endpoint cell painting assays

Multi-endpoint cell painting assays

Our innovative cell painting assays (the _ONE services) deliver multi-endpoint, focused, specific results that delve deeper and support mechanistic understanding

Unique products

Unique products

Our patented products ImmuPHAGE™ and ImmuLUNG™ provide a detailed understanding of the human immune system’s response to various chemicals
Our bespoke services offer a personalised, human-relevant in vitro solution that uniquely addresses your risk assessment needs
Our innovative cell painting assays (the _ONE services) deliver multi-endpoint, focused, specific results that delve deeper and support mechanistic understanding
Our patented products ImmuPHAGE™ and ImmuLUNG™ provide a detailed understanding of the human immune system’s response to various chemicals

Why is it important?

We take 23,000 breaths per day, and with each breath we inhale a combination of airborne chemicals – for example pollution, perfume, household sprays, inhaled medications for managing allergies and lung diseases such as asthma. However, as a society we are increasingly aware of the impact that such chemicals can have on our health. Regulators oblige the industries that develop and manufacture chemical products – including pharmaceuticals, agrichemicals, chemicals and consumer products – to carry out increasingly stringent risk assessments. But such risk assessments often require a large amount of animal trials, which are time-consuming, costly and unpopular. Another problem is that risk assessments are often binary – with either a “good” outcome or a “bad” one.

ImmuONE provides a solution – a cost-effective, multi-endpoint alternative which is more human-relevant and reduces animal testing, exploring various interpretations of a read-out.

We are experts in the lung’s immune system – in particular, the alveolar macrophages which are the first to respond when a chemical enters the respiratory system. Our services, products and experts can accurately predict the immune system’s response in the lungs.

Our unique in vitro models and multi-endpoint assessments deliver results spanning morphology, function and biochemistry to provide companies with clarity on the human health impact of their products.

HOW WE WORK WITH CUSTOMERS

In vitro services for inhalation testing

We have developed novel in vitro products – ImmuPHAGE™ and ImmuLUNG™ – that reveal the interactions between lung alveolar cells, macrophages, and epithelial cells.

In vitro alveolar macrophage assays

With our guidance, we can help you to determine the lung toxicity of any substance.

Immune-competent in vitro human airways models

Via our scientific consultancy services, we can work with you to understand the problem that you need solved, and determine whether our cutting-edge innovative products and services can help you to reach your goals.

Applications

Chemicals

Cosmetics

Crop Protection

Environment

The standard product comes as a 24-well plate, though other
formats are available on request

For more information

Email us at info@immuone.com

News Articles

Our Scientific Lead in Genetic Toxicology, meet Dr Verma!

Dr. Verma joins us for a coffee to share his diverse journey from studying human and medical genetics to his groundbreaking work in genetic toxicology. Discover what drives Dr. Verma’s dedication to developing new genetic toxicity testing at ImmuONE.

ImmuONE featured on ITV News

Gender equality in the biotech industry has come a long way in recent years. In the UK, the US and Europe, women now make up between 40-50% of the biotech workforce, which is a higher percentage than in other STEM fields, such as engineering and the physical sciences.

From microbiology to biotech: Meet Brendon

Brendon Ghiot, our Senior Scientist at ImmuONE, joins us for a coffee to share his diverse journey from working in cellular biology to pioneering in CAR-T therapy for cancer treatment. Brendon tells us what drives his interest in developing new technologies at ImmuONE, particularly in animal-free inhalation toxicity testing.

Scroll to Top